“Dare I Say It”: Psychedelics in Oncology With Daniel

On this week's episode, Accelerator Dr. Simul Parikh hosts Radiation Oncologist Dr. Daniel Koffler to discuss psychedelics in oncology!

They kick off the conversation by discussing ketamine. They review it's use in head and neck and gynecologic cancers, and discuss two trials by Daniel and colleagues (see below).

Later, they discuss the systemic use of psychedelics, some practical advice for incorporating psychedelics (topical and systemic) and collaborating with psychiatrists and psychologists in your local practice.

Here are some things discussed during the show as well as some more stuff you should check out:

• Clinical trial of ketamine mouthwash by Daniel and friends (get the protocol)
• Clinical trial of ketamine psychotherapy (KAPTIVATED) by the same
• Analgesic effects of topical ketamine, a review
• Treatment of severe mucositis pain with oral ketamine mouthwash
• Topical Ketamine in the Treatment of Mucositis Pain, a dramatic case report
• "Finding medical value in mescaline" in Nature
• Efficacy of ketamine therapy in the treatment of depression
• Efficacy of Esketamine Nasal Spray Plus Oral Antidepressant Treatment for Relapse Prevention in Depression

(Editor's Book Recommendation! For an excellent book on the history of psychedelics research and their resurgence, check out How To Change Your Mind by Michael Pollen)

Podcast art generously donated by Dr. Danielle Cunningham. Intro and Outro music by Emmy-award winning artist Lucas Cantor Santiago.

The Accelerators Podcast is a Photon Media production.